Partial liquid ventilation: effects of liquid volume and ventilatory settings on perfluorocarbon evaporation

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Partial liquid ventilation: effects of liquid volume and ventilatory settings on perfluorocarbon evaporation.

During partial liquid ventilation perfluorocarbons are eliminated mainly by evaporation via the airways. The effects of intrapulmonary perfluorocarbon volume, respiratory rate, tidal volume, as well as the level of end-expiratory pressure on perfluorocarbon elimination from isolated lungs, were studied. Nonperfused rabbit lungs underwent partial liquid ventilation (2-15 mL x kg(-1) perfluorocar...

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Does perfluorocarbon deoxygenate during partial liquid ventilation?

Perfluorocarbons accumulate in the dependent regions of the lungs, which may result in regional hypoxia if ventilation with oxygen is insufficient to oxygenate the dependent perfluorocarbon-filled alveoli. In this issue of Critical Care, Max et al present data that demonstrate a decrease in arterial oxygen tension (PaO2) at 30 min compared to that observed at 5 min after administration of FC 32...

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Commentary Does perfluorocarbon deoxygenate during partial liquid ventilation?

Perfluorocarbons accumulate in the dependent regions of the lungs, which may result in regional hypoxia if ventilation with oxygen is insufficient to oxygenate the dependent perfluorocarbon-filled alveoli. In this issue of Critical Care, Max et al present data that demonstrate a decrease in arterial oxygen tension (PaO2) at 30 min compared to that observed at 5 min after administration of FC 32...

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Vaporized perfluorocarbon: taking the "liquid" out of liquid ventilation.

ALTHOUGH only a relatively limited amount of oxygen is dissolved in water under natural conditions, aquatic creatures enjoy great success in extracting sufficient amounts to meet the metabolic demands of life. Mammals (even aquatic mammals) avoid this limitation by using atmospheric oxygen through specialized gas exchange mechanisms in the lung. However, the niammalian lung can also extract suf...

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Partial liquid ventilation.

Correspondence: B. Lachmann, Dept of Anesthesiology (Room Ee 2393), Erasmus University Rotterdam, Postbox 1738, 3000 DR Rotterdam, The Netherlands. There is strong indication that modes of ventilation that lead to repeated closure and opening of surfactantdeficient alveoli can induce severe functional and histological lung damage [1]. New modes of ventilation are directed at prevention of lung ...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2002

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.02.00299002